3-Nitrochalcone is primarily utilized in organic synthesis and research due to its unique chemical structure, which makes it a valuable intermediate in the preparation of various heterocyclic compounds. It is often employed in the development of pharmaceuticals, particularly in the synthesis of compounds with potential anti-inflammatory, anticancer, and antimicrobial properties. Additionally, its nitro group makes it a useful precursor in the study of nitro-reduction reactions, which are important in drug metabolism and environmental chemistry. In material science, 3-Nitrochalcone is explored for its potential in creating organic electronic materials and light-sensitive compounds. Its application in photochemical studies is also notable, as it can be used to investigate photo-induced reactions and molecular interactions.