4'-Chlorochalcone is primarily utilized in the field of organic synthesis and medicinal chemistry. It serves as a key intermediate in the development of various pharmaceutical compounds, particularly those targeting anti-inflammatory and anticancer properties. Researchers have explored its potential in inhibiting specific enzymes and pathways involved in disease progression. Additionally, it is used in the study of structure-activity relationships to optimize the efficacy of drug candidates. Its application extends to material science, where it is investigated for its photophysical properties, making it a candidate for use in organic electronic devices.