4-Fluorochalcone is used in organic synthesis to create complex molecules for pharmaceutical research. It acts as an intermediate in the development of drugs targeting inflammation, cancer, and neurological disorders such as Alzheimer's disease, where it may reduce the accumulation of beta-amyloid protein in the brain. It is studied for its potential antioxidant, antimicrobial, antibacterial, and antifungal properties, which could lead to new antimicrobial agents. Additionally, it is applied in material science for designing fluorescent probes and sensors, and explored in agrochemical research for developing crop protection agents.