Used as a highly selective ionophore in chemical sensors, particularly for the detection of alkali and alkaline earth metal ions in aqueous and mixed solvent systems. Its crown ether-like structure enables strong complexation with specific cations, making it valuable in potentiometric membrane electrodes for environmental monitoring and clinical diagnostics. Also employed in supramolecular chemistry for designing host-guest systems due to its rigid, multi-dentate framework that enhances binding specificity. Additionally, serves as a building block in metal-organic frameworks (MOFs) where its carboxylic acid groups facilitate coordination with metal nodes, contributing to porous materials for ion exchange or sensing applications.