Dimethylglyoxime is widely used in analytical chemistry as a reagent for the detection and quantification of nickel and palladium. It forms a bright red precipitate with nickel ions, making it a key component in qualitative and quantitative analysis of nickel-containing samples. This property is particularly useful in industries such as metallurgy, where it helps determine nickel content in alloys and ores. Additionally, it is employed in organic synthesis as a chelating agent to isolate and purify specific metal ions. Its ability to form stable complexes with metals also finds applications in electroplating and corrosion inhibition processes.