Macropa-NH2 is primarily used in the field of radiopharmaceuticals, particularly in the development of targeted alpha therapy. Its high affinity for actinium-225 and other alpha-emitting radionuclides makes it an excellent chelator for creating stable complexes. These complexes are utilized in cancer treatment, where they deliver targeted radiation to tumor cells while minimizing damage to healthy tissues. Additionally, Macropa-NH2 is employed in diagnostic imaging, enabling precise visualization of diseased areas. Its stability and selectivity also make it valuable in research applications, such as studying the behavior of radionuclides in biological systems.