Ammonium citrate tribasic is widely used in various industries due to its versatile properties. In the food industry, it serves as an emulsifying agent and acidity regulator, particularly in dairy products and baked goods. It helps stabilize textures and enhance flavors. In the pharmaceutical sector, it is utilized as a buffering agent in medications to maintain pH levels and improve drug stability.

In industrial applications, it is commonly employed as a cleaning agent for metal surfaces, effectively removing rust and scale without causing corrosion. It is also used in water treatment processes to prevent the formation of scale in boilers and cooling systems. Additionally, ammonium citrate tribasic finds use in analytical chemistry as a reagent for complexometric titrations, aiding in the determination of metal ions in solutions. Its ability to chelate metals makes it valuable in various chemical processes and formulations.