CXCR2-IN-1 is primarily used in research settings to study the role of CXCR2 receptors in various biological processes. It serves as a potent and selective inhibitor of the CXCR2 receptor, which is involved in mediating inflammatory responses. By blocking CXCR2, this compound helps researchers investigate its impact on neutrophil migration, a key factor in inflammation and immune responses. It is particularly useful in exploring potential therapeutic strategies for inflammatory diseases, such as chronic obstructive pulmonary disease (COPD), asthma, and rheumatoid arthritis. Additionally, CXCR2-IN-1 is employed in cancer research to study the role of CXCR2 in tumor microenvironment regulation and metastasis. Its application extends to understanding the mechanisms of chemokine signaling pathways and their implications in disease progression.