D-Homophenylalanine tert-Butyl Ester is primarily utilized in the synthesis of peptides and pharmaceutical intermediates. Its tert-butyl ester group serves as a protective group for carboxylic acids, enabling selective reactions in complex organic syntheses. This compound is particularly valuable in the production of chiral molecules, where it aids in maintaining stereochemical integrity during chemical transformations. It is also employed in the development of bioactive compounds, including enzyme inhibitors and receptor ligands, due to its ability to introduce specific structural motifs. Additionally, it finds use in medicinal chemistry for the preparation of drug candidates targeting various therapeutic areas.