[bis[3,5-bis(trifluoromethyl)phenyl]-[(2R)-pyrrolidin-2-yl]methoxy]-trimethylsilane
>=95%, ee 99%
Reagent
Code: #88243
CAS Number
908303-26-4
blur_circular Chemical Specifications
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Molecular Information
Weight
597.52 g/mol
Formula
C₂₄H₂₃F₁₂NOSi
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Registry Numbers
MDL Number
MFCD09750448
thermostat
Physical Properties
Boiling Point
382.4°C
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Storage & Handling
Density
1.319g/mL
Storage
room temperature, dry
description Product Description
This compound is primarily utilized in asymmetric synthesis and catalysis, particularly in organic transformations where high enantioselectivity is required. It serves as a chiral ligand or catalyst in various reactions, such as asymmetric hydrogenation, carbon-carbon bond formation, and other stereoselective processes. Its trifluoromethyl groups enhance electron-withdrawing properties, improving reactivity and selectivity in catalytic systems. Additionally, the trimethylsilane moiety provides stability and facilitates handling in synthetic applications. It is often employed in the pharmaceutical industry for the synthesis of chiral intermediates or active pharmaceutical ingredients (APIs) with high optical purity.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | White to beige and faint brown to brown powder or crystal or chunk(s) |
| Infrared Spectrum | Conforms to Structure |
| Purity | 95-100% |
| e.e. | 98-100% |
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