(4R,5S)-2-((S)-1-(Diphenylphosphanyl)piperidin-2-yl)-4,5-diphenyl-4,5-dihydrooxazole

97%

Reagent Code: #229498
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CAS Number 2757084-55-0

science Other reagents with same CAS 2757084-55-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 490.58 g/mol
Formula C₃₂H₃₁N₂OP
thermostat Physical Properties
Boiling Point 622.1±65.0 °C(Predicted)
inventory_2 Storage & Handling
Storage 2-8°C, light-proof, inert gas

description Product Description

Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective transformations such as hydrogenation and transfer hydrogenation of prochiral ketones and imines. Its rigid oxazoline-piperidine backbone and diphenylphosphine group make it highly effective in coordinating transition metals like ruthenium, rhodium, and iridium, forming catalysts that deliver high enantiomeric excess. It is particularly valued in pharmaceutical synthesis where precise stereochemical control is critical. The ligand’s structure allows for fine tuning of steric and electronic properties, enhancing selectivity in complex molecule construction.

Available Sizes & Pricing

Size Availability Unit Price Quantity
50mg
10-20 days ฿6,800.00
100mg
10-20 days ฿11,550.00
250mg
10-20 days ฿19,640.00
(4R,5S)-2-((S)-1-(Diphenylphosphanyl)piperidin-2-yl)-4,5-diphenyl-4,5-dihydrooxazole
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Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective transformations such as hydrogenation and transfer hydrogenation of prochiral ketones and imines. Its rigid oxazoline-piperidine backbone and diphenylphosphine group make it highly effective in coordinating transition metals like ruthenium, rhodium, and iridium, forming catalysts that deliver high enantiomeric excess. It is particularly valued in pharmaceutical synthesis where precise stereochemical control is critical. The ligand’s structure allows for fine tuning of steric and electronic properties, enhancing selectivity in complex molecule construction.
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