(4S)-2-[(1R)-7'-(Diphenylphosphino)-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-inden]-7-yl]-4,5-dihydro-4-(phenylmethyl)oxazole
≥95%,99%e.e.
Reagent
Code: #59714
blur_circular Chemical Specifications
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Molecular Information
Weight
563.7 g/mol
Formula
C₃₉H₃₄NOP
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Storage & Handling
Storage
room temperature, dry
description Product Description
This chemical is primarily utilized as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions. Its unique structure, featuring a spirobiindane backbone and a diphenylphosphino group, makes it highly effective in inducing enantioselectivity. It is commonly employed in hydrogenation reactions, where it helps produce chiral molecules with high enantiomeric excess. Additionally, it is used in cross-coupling reactions, such as Suzuki-Miyaura and Heck reactions, to synthesize complex organic compounds with precise stereochemistry. Its application extends to the pharmaceutical industry, where it aids in the production of enantiomerically pure drugs and intermediates. The ligand's stability and selectivity make it a valuable tool in organic synthesis for creating high-value chiral products.
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(4S)-2-[(1R)-7'-(Diphenylphosphino)-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-inden]-7-yl]-4,5-dihydro-4-(phenylmethyl)oxazole
This chemical is primarily utilized as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions. Its unique structure, featuring a spirobiindane backbone and a diphenylphosphino group, makes it highly effective in inducing enantioselectivity. It is commonly employed in hydrogenation reactions, where it helps produce chiral molecules with high enantiomeric excess. Additionally, it is used in cross-coupling reactions, such as Suzuki-Miyaura and Heck reactions, to synthesize complex organic compounds with precise stereochemistry. Its application extends to the pharmaceutical industry, where it aids in the production of enantiomerically pure drugs and intermediates. The ligand's stability and selectivity make it a valuable tool in organic synthesis for creating high-value chiral products.
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