S-()-1,1'-Binaphthyl-2,2'-diyl hydrogen phosphate is widely used as a chiral resolving agent in the separation of enantiomers, particularly in pharmaceutical and chemical research. It is effective in forming diastereomeric salts with racemic mixtures, enabling the purification of optically active compounds. This chemical is also employed in asymmetric synthesis as a chiral catalyst or ligand, facilitating the production of enantiomerically pure substances. Additionally, it finds application in the development of chiral stationary phases for high-performance liquid chromatography (HPLC), enhancing the separation efficiency of chiral molecules. Its role in these processes is crucial for advancing drug development and ensuring the production of high-purity chiral compounds.