Used as a chiral bidentate ligand in asymmetric catalysis, particularly in rhodium- and ruthenium-catalyzed enantioselective hydrogenation reactions. It is highly effective in the synthesis of chiral compounds, especially in pharmaceuticals and fine chemicals where high enantiomeric excess is required. Its rigid backbone and well-defined stereochemistry enhance selectivity and reaction efficiency. Commonly applied in the hydrogenation of prochiral olefins, ketones, and imines, enabling the production of optically active intermediates used in drug development and agrochemicals.