N-[(11bR)-(2,6-Bis(4-(naphthalen-2-yl)phenyl)-4-oxido-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl)]-1,1,1-trifluoromethanesulfonamide
98%
science Other reagents with same CAS 2586125-72-4
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description Product Description
Used as a chiral organocatalyst in asymmetric synthesis, particularly in enantioselective transformations such as aldol reactions, Michael additions, and Diels-Alder cyclizations. Its rigid, sterically hindered structure with a defined phosphine oxide center enables high stereocontrol, making it valuable in pharmaceutical and fine chemical synthesis where precise chirality is critical. The compound’s strong electron-withdrawing triflyl group enhances catalytic activity by increasing acidity and stabilizing transition states. It is especially effective in reactions requiring Brønsted acid or hydrogen-bond-donor catalysis.
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