Chloromethyl ethyl carbonate
97%
Reagent
Code: #159972
CAS Number
35179-98-7
blur_circular Chemical Specifications
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Molecular Information
Weight
138.55 g/mol
Formula
C₄H₇ClO₃
thermostat
Physical Properties
Boiling Point
135.1°C
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Storage & Handling
Storage
2-8°C
description Product Description
Used as an alkylating agent in organic synthesis, particularly in the protection and modification of hydroxyl groups in pharmaceutical intermediates. It serves as a reagent for introducing the ethoxycarbonyloxymethyl (EOM) protecting group, which is useful in peptide and nucleotide synthesis. Its reactivity allows selective functionalization under mild conditions, making it valuable in the development of active pharmaceutical ingredients (APIs). Also employed in the preparation of prodrugs due to its ability to form carbonate esters that can be metabolically cleaved.
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