Chlorodiethylphosphine is primarily used in the synthesis of organophosphorus compounds, which are essential in various industrial and research applications. It serves as a key precursor in the production of phosphine ligands, which are widely employed in coordination chemistry and catalysis. These ligands play a crucial role in facilitating reactions in organic synthesis, including cross-coupling reactions and polymerization processes. Additionally, it is utilized in the development of flame retardants, where organophosphorus compounds are incorporated into materials to enhance fire resistance. The chemical also finds applications in the preparation of pesticides and herbicides, contributing to agricultural practices by controlling pests and weeds effectively. Its reactivity and versatility make it a valuable component in the field of chemical research and industrial manufacturing.