Used as a silylating agent in organic synthesis, particularly for the protection of hydroxyl groups in alcohols and phenols. It is effective in introducing the diisopropylsilyl (iPr2Si) protecting group, which offers good stability under a variety of reaction conditions while being selectively removable. This makes it valuable in multi-step syntheses, especially in the preparation of complex molecules like natural products and pharmaceuticals. Its steric bulk helps control regioselectivity during functional group transformations. Also employed in the modification of silica surfaces and in the production of silicone-based polymers due to its reactivity with hydroxylated materials.