Acetylcholinesterase
Biotech grade, 220u/mg
Reagent
Code: #98871
CAS Number
9000-81-1
blur_circular Chemical Specifications
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Registry Numbers
MDL Number
MFCD00081268
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Storage & Handling
Storage
-20°C
description Product Description
Acetylcholinesterase (AChE) is an enzyme that catalyzes the hydrolysis of the neurotransmitter acetylcholine into choline and acetic acid, terminating signal transmission at cholinergic synapses. This biotech-grade lyophilized powder (220 U/mg) is primarily used as a reagent in laboratory and research settings.
- Biochemical Assays: Essential for enzymatic activity assays, such as Ellman's method, to measure AChE levels in samples for neuroscience and toxicology studies.
- Medical Diagnostics and Research: Employed in vitro to screen inhibitors for treating Alzheimer's disease, myasthenia gravis, and glaucoma; aids in studying neurological disorders and developing therapeutics.
- Agricultural Applications: Used to test the efficacy of organophosphate and carbamate pesticides by assessing inhibition of insect AChE.
- Toxicology and Safety: Critical for evaluating exposure to nerve agents (e.g., sarin) and organophosphates, supporting antidote development and poisoning diagnostics.
AChE reagents enable precise neurobiological research and high-throughput screening for pharmaceutical and agrochemical innovations.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | Lyophilized powder |
| Activity (U/mg) | 220 |
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