N,O-Bis(trimethylsilyl)acetamide (TMS-BA)
95%
- Product Code: 93725
Alias:
N,O-bis(trimethylsilyl)acetamide ; N,O-bistrimethylsilylacetamide
CAS:
10416-59-8
Molecular Weight: | 203.43 g./mol | Molecular Formula: | C₈H₂₁NOSi₂ |
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EC Number: | 233-892-7 | MDL Number: | MFCD00008270 |
Melting Point: | 24 °C | Boiling Point: | 71-73 °C/35 mmHg(lit.) |
Density: | 0.832 g/mL at 20 °C(lit.) | Storage Condition: | 2~8°C |
Product Description:
Used extensively in organic synthesis as a silylating agent, it effectively protects hydroxyl, amino, and carboxyl groups during chemical reactions. It is particularly valuable in the preparation of sensitive intermediates where selective protection is required. In pharmaceuticals, it aids in the synthesis of complex drug molecules by ensuring stability and reactivity of functional groups. Additionally, it is employed in the derivatization of compounds for gas chromatography and mass spectrometry, enhancing volatility and detectability of analytes. Its role in peptide synthesis is also notable, where it facilitates the modification of amino acids to improve reaction efficiency.
Product Specification:
Test | Specification |
---|---|
Purity | 95-100 |
REFRACTIVE INDEX 20C | 1.416-1.419 |
SPECIFIC GRAVITY 2020C | 0.831-0.833 |
APPEARANCE | Colorless to light yellow liquid |
INFRARED SPECTRUM | Conforms to Structure |
NOTE: | This product is low melting point solid,may change state in different environments (solid, liquid or semi-solid) |
Sizes / Availability / Pricing:
Size (g) | Availability | Price | Quantity |
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5.000 | 10-20 days | ฿300.00 |
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25.000 | 10-20 days | ฿410.00 |
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100.000 | 10-20 days | ฿870.00 |
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500.000 | 10-20 days | ฿2,880.00 |
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2500.000 | 10-20 days | ฿13,680.00 |
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N,O-Bis(trimethylsilyl)acetamide (TMS-BA)
Used extensively in organic synthesis as a silylating agent, it effectively protects hydroxyl, amino, and carboxyl groups during chemical reactions. It is particularly valuable in the preparation of sensitive intermediates where selective protection is required. In pharmaceuticals, it aids in the synthesis of complex drug molecules by ensuring stability and reactivity of functional groups. Additionally, it is employed in the derivatization of compounds for gas chromatography and mass spectrometry, enhancing volatility and detectability of analytes. Its role in peptide synthesis is also notable, where it facilitates the modification of amino acids to improve reaction efficiency.
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