N,O-Bis(trimethylsilyl)acetamide (TMS-BA)

95%

  • Product Code: 93725
  Alias:    N,O-bis(trimethylsilyl)acetamide ; N,O-bistrimethylsilylacetamide
  CAS:    10416-59-8
Molecular Weight: 203.43 g./mol Molecular Formula: C₈H₂₁NOSi₂
EC Number: 233-892-7 MDL Number: MFCD00008270
Melting Point: 24 °C Boiling Point: 71-73 °C/35 mmHg(lit.)
Density: 0.832 g/mL at 20 °C(lit.) Storage Condition: 2~8°C
Product Description: Used extensively in organic synthesis as a silylating agent, it effectively protects hydroxyl, amino, and carboxyl groups during chemical reactions. It is particularly valuable in the preparation of sensitive intermediates where selective protection is required. In pharmaceuticals, it aids in the synthesis of complex drug molecules by ensuring stability and reactivity of functional groups. Additionally, it is employed in the derivatization of compounds for gas chromatography and mass spectrometry, enhancing volatility and detectability of analytes. Its role in peptide synthesis is also notable, where it facilitates the modification of amino acids to improve reaction efficiency.
Product Specification:
Test Specification
Purity 95-100
REFRACTIVE INDEX 20C 1.416-1.419
SPECIFIC GRAVITY 2020C 0.831-0.833
APPEARANCE Colorless to light yellow liquid
INFRARED SPECTRUM Conforms to Structure
NOTE: This product is low melting point solid,may change state in different environments (solid, liquid or semi-solid)
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
5.000 10-20 days ฿300.00
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25.000 10-20 days ฿410.00
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100.000 10-20 days ฿870.00
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-
500.000 10-20 days ฿2,880.00
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-
2500.000 10-20 days ฿13,680.00
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N,O-Bis(trimethylsilyl)acetamide (TMS-BA)
Used extensively in organic synthesis as a silylating agent, it effectively protects hydroxyl, amino, and carboxyl groups during chemical reactions. It is particularly valuable in the preparation of sensitive intermediates where selective protection is required. In pharmaceuticals, it aids in the synthesis of complex drug molecules by ensuring stability and reactivity of functional groups. Additionally, it is employed in the derivatization of compounds for gas chromatography and mass spectrometry, enhancing volatility and detectability of analytes. Its role in peptide synthesis is also notable, where it facilitates the modification of amino acids to improve reaction efficiency.
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