Used as a reference standard in analytical testing to quantify (-)-Epicatechin levels in natural products like cocoa, green tea, and dietary supplements. Widely applied in HPLC and LC-MS methods for quality control in pharmaceuticals, nutraceuticals, and food and beverage industries. Supports research on flavonoid bioavailability, antioxidant activity, and potential cardiovascular and metabolic health benefits. Ensures accuracy and reproducibility in concentration measurements during method validation and routine analysis.