Used primarily to treat orthostatic hypotension, midodrine hydrochloride helps increase blood pressure when standing up, reducing dizziness, lightheadedness, and risk of fainting. It works by constricting blood vessels, improving blood flow back to the heart and enhancing circulation in upright positions. Commonly prescribed for patients with autonomic nervous system disorders, it is taken orally and provides short-term symptomatic relief, typically during daytime hours to support mobility and daily activities.