Widely used in RNA isolation protocols, especially from plant tissues and other difficult biological samples. Effectively lyses cells and disrupts membranes while inhibiting RNase activity that can degrade RNA. Particularly useful for extracting high-quality, intact RNA from samples rich in polysaccharides, polyphenols, and secondary metabolites. Commonly applied in molecular biology research, gene expression studies, and RT-PCR, where RNA purity and integrity are critical. Also compatible with downstream applications such as Northern blotting and RNA sequencing.