Buflomedil HCl is primarily used in the treatment of peripheral vascular diseases, such as intermittent claudication, which is characterized by pain during walking due to poor blood circulation in the legs. It works by improving blood flow, particularly in the small vessels, and enhancing oxygen supply to the affected tissues. This makes it effective in alleviating symptoms like pain, cramping, and numbness in the limbs.

Additionally, Buflomedil HCl is sometimes prescribed for conditions related to cerebral vascular insufficiency, where it helps in improving cognitive functions and reducing symptoms like dizziness and memory loss by enhancing cerebral blood flow. Its vasodilatory properties also make it useful in managing certain types of tinnitus and vertigo associated with vascular issues.

In clinical settings, it is administered orally or intravenously, depending on the severity of the condition and the patient's response to treatment. Regular monitoring is essential to ensure efficacy and to manage any potential side effects.