3-Chloro-4-fluorocinnamic acid is widely used in organic synthesis as a building block for the preparation of more complex molecules. It serves as a key intermediate in the development of pharmaceuticals, particularly in the synthesis of compounds with potential anti-inflammatory, antimicrobial, and anticancer properties. Its structure, featuring both chloro and fluoro substituents, makes it valuable for studying structure-activity relationships in drug design. Additionally, it is employed in material science for the development of organic electronic materials, such as organic light-emitting diodes (OLEDs), due to its conjugated system that can enhance electronic properties. In research, it is also utilized as a model compound in studies involving photochemical reactions and polymerization processes.