4-((tert-Butyldimethylsilyl)oxy)but-2-ynoic acid

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Reagent Code: #46046
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CAS Number 102245-65-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 214.3336 g/mol
Formula C₁₀H₁₈O₃Si
badge Registry Numbers
MDL Number MFCD06658386
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

This compound, 4-((tert-Butyldimethylsilyl)oxy)but-2-ynoic acid, is a specialized intermediate in organic synthesis. It features a hydroxyl group protected as a tert-butyldimethylsilyl (TBDMS) ether at the 4-position, which shields it during reactions involving the carboxylic acid or the terminal alkyne. The alkyne moiety enables efficient participation in click chemistry, such as azide-alkyne cycloadditions, for building complex structures. This makes it valuable for the synthesis of pharmaceuticals, natural products, bioactive compounds, and advanced materials, where selective protection and modular assembly are essential.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿4,630.00

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