4-((tert-Butyldimethylsilyl)oxy)but-2-ynoic acid
98%
Reagent
Code: #46046
CAS Number
102245-65-8
blur_circular Chemical Specifications
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Molecular Information
Weight
214.3336 g/mol
Formula
C₁₀H₁₈O₃Si
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Registry Numbers
MDL Number
MFCD06658386
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Storage & Handling
Storage
2-8°C
description Product Description
This compound, 4-((tert-Butyldimethylsilyl)oxy)but-2-ynoic acid, is a specialized intermediate in organic synthesis. It features a hydroxyl group protected as a tert-butyldimethylsilyl (TBDMS) ether at the 4-position, which shields it during reactions involving the carboxylic acid or the terminal alkyne. The alkyne moiety enables efficient participation in click chemistry, such as azide-alkyne cycloadditions, for building complex structures. This makes it valuable for the synthesis of pharmaceuticals, natural products, bioactive compounds, and advanced materials, where selective protection and modular assembly are essential.
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