4-[(5-aza-3,4:7,8-dibenzocyclooctan-1-yne)-5-yl]-4-oxobutyrate-n-succinimide
98%
Reagent
Code: #46728
CAS Number
1353016-71-3
blur_circular Chemical Specifications
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Molecular Information
Weight
402.40 g/mol
Formula
C₂₃H₁₈N₂O₅
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Registry Numbers
MDL Number
MFCD24386367
thermostat
Physical Properties
Boiling Point
670.2±65.0 °C at 760 mmHg
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Storage & Handling
Density
1.43±0.1 g/cm3
Storage
2-8℃
description Product Description
This chemical is primarily utilized in bioconjugation and protein labeling due to its reactive succinimide ester group, which facilitates covalent bonding with primary amines in proteins, peptides, and other biomolecules. It is particularly valuable in the development of antibody-drug conjugates (ADCs) for targeted cancer therapies, where it enables the precise attachment of cytotoxic agents to antibodies. Additionally, it is employed in fluorescence labeling for imaging and diagnostic applications, allowing researchers to track and visualize biological processes in real-time. Its unique structure also makes it suitable for crosslinking studies in biochemistry, aiding in the investigation of protein-protein interactions and molecular structures.
format_list_bulleted Product Specification
Test Parameter | Specification |
---|---|
Appearance | White to off-white solid |
Purity | 97.5-100 |
Infrared Spectrum | Conforms to Structure |
NMR | Conforms to Structure |
shopping_cart Available Sizes & Pricing
4-[(5-aza-3,4:7,8-dibenzocyclooctan-1-yne)-5-yl]-4-oxobutyrate-n-succinimide
This chemical is primarily utilized in bioconjugation and protein labeling due to its reactive succinimide ester group, which facilitates covalent bonding with primary amines in proteins, peptides, and other biomolecules. It is particularly valuable in the development of antibody-drug conjugates (ADCs) for targeted cancer therapies, where it enables the precise attachment of cytotoxic agents to antibodies. Additionally, it is employed in fluorescence labeling for imaging and diagnostic applications, allowing researchers to track and visualize biological processes in real-time. Its unique structure also makes it suitable for crosslinking studies in biochemistry, aiding in the investigation of protein-protein interactions and molecular structures.
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