Thrombin is widely used in medical and surgical applications due to its role in blood clotting. It is commonly applied as a topical hemostatic agent to control bleeding during surgeries, particularly in procedures involving highly vascular tissues like the liver, spleen, or vascular surgeries. In dental procedures, thrombin is used to manage bleeding in extraction sites or oral surgeries. It is also a key component in fibrin sealants, which are used to promote wound healing and tissue adhesion in various surgical settings, including orthopedic, cardiovascular, and neurosurgical procedures. Additionally, thrombin is utilized in diagnostic laboratories for coagulation tests to assess blood clotting disorders. Its ability to rapidly convert fibrinogen into fibrin makes it indispensable in both therapeutic and diagnostic contexts.