Used in research settings to study adrenal steroid metabolism and its effects on immune function, stress response, and inflammation. Acts as a synthetic derivative of corticosterone, allowing scientists to investigate the role of glucocorticoids in cellular and animal models. Due to its acetylated form at the 21-position, it may exhibit altered solubility or metabolic stability compared to the parent compound, making it useful in pharmacokinetic studies or in designing prodrugs. Also employed in endocrinology assays to calibrate detection methods for steroid hormones. Its ability to penetrate cell membranes facilitates direct intracellular action in experimental models.