Diflorasone is primarily used in dermatology for its potent anti-inflammatory, antipruritic, and vasoconstrictive properties. It is commonly applied topically to treat various skin conditions such as eczema, psoriasis, and allergic dermatitis. The chemical helps reduce redness, swelling, and itching associated with these conditions. It is often prescribed for short-term use on affected areas to manage severe symptoms effectively. Due to its high potency, it is typically reserved for cases where milder corticosteroids have proven ineffective. Careful application is advised to avoid potential side effects like skin thinning or irritation.