Betamethasone 17-butyrate 21-propionate is a synthetic glucocorticoid and a specialty chemical used as an active pharmaceutical ingredient (API) in dermatological formulations. It exhibits potent anti-inflammatory, antipruritic, and immunosuppressive effects, making it effective for treating skin conditions such as eczema, psoriasis, and dermatitis by reducing inflammation, itching, and redness. This high-purity compound (≥98%) is applied topically in creams, ointments, or lotions for localized therapy, particularly in severe or corticosteroid-resistant cases. It serves as an intermediate in pharmaceutical synthesis and is suitable for research, development, and manufacturing of topical steroids. Adherence to safety guidelines is crucial to avoid side effects like skin atrophy when formulated products are used.