Used as a peptide coupling reagent in organic synthesis, particularly in the preparation of complex peptides and pharmaceutical intermediates. Its trifluoroacetic acid salt form enhances solubility in polar solvents, improving reaction efficiency in solid-phase peptide synthesis. Commonly applied in research settings for synthesizing bioactive peptides with high purity and yield. Also utilized in the development of peptide-based drugs and diagnostics due to its stability and compatibility with sensitive functional groups.