Used as a crosslinking agent in biochemistry and molecular biology to study protein-protein interactions. It facilitates the formation of covalent bonds between primary amines, enabling the stabilization of protein complexes for analysis. Commonly applied in immunoprecipitation experiments to preserve protein interactions during cell lysis. Also utilized in the preparation of affinity chromatography matrices, where it helps immobilize proteins or ligands onto solid supports. Its water-soluble nature makes it suitable for use in aqueous solutions, ensuring efficient crosslinking in biological samples.