Used as a selective complexing agent for lithium ions in analytical chemistry and separation processes. Its cavity size allows it to form stable complexes with small cations, especially Li⁺, making it useful in ion-selective electrodes and sensors. Employed in organic synthesis to enhance reactivity and solubility of lithium salts in nonpolar solvents. Also applied in phase-transfer catalysis, where it facilitates the transfer of ionic species into organic phases, improving reaction efficiency. Investigated for use in lithium battery electrolytes to stabilize lithium ions and improve ion conductivity.