Used as a selective ionophore in ion-selective electrodes, particularly for detecting large cations like ammonium, rubidium, and cesium due to its high binding affinity. Employed in supramolecular chemistry to form host-guest complexes, enabling molecular recognition and self-assembly processes. Applied in separation technologies for selective extraction of metal ions from mixtures. Serves as a building block in the synthesis of crown ether-based polymers and sensors. Also utilized in catalysis, where it stabilizes cationic species in organic reactions.