Dicyclohexano-18-crown-6 is widely used as a selective complexing agent in various chemical processes. Its primary application is in the extraction and separation of metal ions, particularly potassium and cesium, from complex mixtures. This makes it valuable in nuclear waste treatment, where it helps isolate radioactive isotopes for safe disposal. Additionally, it is employed in ion-selective electrodes to improve their sensitivity and selectivity for specific cations. In organic synthesis, it acts as a phase-transfer catalyst, facilitating reactions between compounds in different phases. Its ability to form stable complexes with certain ions also finds use in analytical chemistry for detecting and quantifying metal ions in samples.