Ethyl 3-fluorocyclobutane-1-carboxylate
98%
Reagent
Code: #132955
CAS Number
1553990-89-8
blur_circular Chemical Specifications
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Molecular Information
Weight
146.16 g/mol
Formula
C₇H₁₁FO₂
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Registry Numbers
MDL Number
MFCD26727203
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Storage & Handling
Storage
2-8°C, dry
description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the development of bioactive molecules requiring fluorinated cyclobutane scaffolds. The presence of both ester and fluorine functionalities makes it valuable for constructing structurally rigid analogs in medicinal chemistry. It is employed in the preparation of protease inhibitors and receptor modulators where ring strain and fluorination influence metabolic stability and binding affinity. Also utilized in agrochemical research for designing novel active ingredients with enhanced lipophilicity and environmental persistence. The compound serves as a building block in asymmetric synthesis, enabling the introduction of fluorinated four-membered rings into complex targets.
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