Used as a key chiral intermediate in the synthesis of pharmaceuticals, particularly in the development of neuroactive drugs and enzyme inhibitors. Its rigid cyclobutane backbone and fluorine substitution enhance metabolic stability and binding selectivity. Commonly employed in the preparation of compounds targeting central nervous system disorders, including antidepressants and antipsychotics. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies due to its stereochemical defined structure and ability to influence conformational restriction in drug candidates.