Spectrin, derived from human erythrocytes, plays a crucial role in maintaining the structural integrity and flexibility of red blood cells. Its primary application lies in research focused on understanding the mechanical properties of cell membranes and their role in cellular function. Spectrin is widely used in studies investigating cytoskeletal architecture, membrane stability, and the pathophysiology of conditions like hereditary spherocytosis and elliptocytosis, where spectrin defects are implicated. Additionally, it serves as a model protein in biophysical research to explore protein-protein interactions and the assembly of the cytoskeleton. Spectrin's unique properties also make it valuable in developing biomimetic materials and artificial cell membranes for biomedical applications.