Malic Dehydrogenase (oxalacetate-decarboxylating) from chicken liver is primarily used in biochemical research and diagnostic applications. It plays a critical role in studying metabolic pathways, particularly the tricarboxylic acid (TCA) cycle, where it catalyzes the conversion of malate to pyruvate and CO2. This enzyme is employed in assays to measure enzyme activity, understand cellular respiration, and investigate energy production mechanisms in cells. It is also utilized in diagnostic kits to detect metabolic disorders or analyze mitochondrial function. Additionally, it serves as a tool in enzymology studies to explore enzyme kinetics, inhibition, and regulation. Its specificity and efficiency make it valuable in both academic and clinical settings.