Glutathione reductase plays a critical role in maintaining cellular health by reducing oxidized glutathione back to its active form, glutathione. This process is essential for protecting cells from oxidative stress and damage caused by free radicals. In the medical field, it is studied for its potential in treating diseases linked to oxidative stress, such as neurodegenerative disorders, cardiovascular diseases, and certain cancers. Additionally, it is used in research to understand the mechanisms of antioxidant defense systems in the body. In biotechnology, glutathione reductase is utilized in assays to measure antioxidant capacity and to study redox reactions in various biological systems. Its application extends to the development of therapeutic strategies aimed at enhancing the body's natural defense against oxidative damage.