PAMAM dendrimers with an ethylenediamine core are widely used in drug delivery systems due to their unique tree-like branched structure, which allows for precise control over molecular size and surface functionality. This makes them highly effective in encapsulating and delivering therapeutic agents, such as anticancer drugs, to specific target sites in the body, reducing side effects and improving treatment precision. Their ability to form stable complexes with nucleic acids also makes them valuable in gene therapy for delivering DNA or RNA to cells. Additionally, these dendrimers are utilized in diagnostic imaging as contrast agents, enhancing the visualization of tissues and organs.

In the field of nanotechnology, they serve as building blocks for creating advanced materials with tailored properties, including nanostructure fabrication and as catalysts due to their large surface area and customizable functional groups. Their biocompatibility and versatility further extend their applications in biosensors, where they help detect biological molecules with high sensitivity.

Beyond biomedical uses, PAMAM dendrimers are applied in the cosmetics industry as ingredients in skincare products to enhance the penetration of active substances, and in the textile industry to improve fiber quality.

With their diverse properties, these dendrimers are highly promising materials for applications across various scientific and technological fields.