PAMAM dendrimers with an ethylenediamine core are widely used in drug delivery systems due to their well-defined structure and ability to encapsulate or conjugate therapeutic agents. They enhance the solubility and stability of drugs, enabling targeted delivery to specific cells or tissues, particularly in cancer therapy. These dendrimers are also employed in gene delivery, where they complex with nucleic acids to facilitate efficient transfection into cells for genetic engineering or therapeutic purposes. In diagnostics, they serve as carriers for imaging agents, improving contrast in techniques like MRI. Additionally, their surface functionalization allows for applications in biosensors, where they enhance sensitivity and specificity in detecting biomolecules. In material science, they are used to create nanostructured materials with tailored properties for coatings, catalysts, and nanocomposites. Their versatility and biocompatibility make them valuable in various biomedical and industrial applications.