PAMAM dendrimer, ethylenediamine core, generation 4.0 solution
20 wt. % in methanol
Reagent
Code: #94536
CAS Number
163442-67-9
blur_circular Chemical Specifications
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Molecular Information
Weight
14214.17 g/mol
Formula
C₆₂₂H₁₂₄₈N₂₆O₁₂₄
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Registry Numbers
MDL Number
MFCD00197936
thermostat
Physical Properties
Boiling Point
64.7 °C
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Storage & Handling
Density
0.813 g/mL at 25 °C
Storage
2-8°C
description Product Description
PAMAM dendrimer, ethylenediamine core, generation 4.0 solution, is widely used in drug delivery systems due to its ability to encapsulate and transport therapeutic agents. Its highly branched structure allows for efficient loading of drugs, while its surface functional groups can be tailored for targeted delivery to specific cells or tissues. This makes it particularly useful in cancer therapy, where precise delivery of chemotherapeutic agents is critical to minimize side effects.
In gene therapy, it serves as a non-viral vector for delivering nucleic acids, such as DNA or RNA, into cells. Its positive surface charge facilitates binding with negatively charged genetic material, enabling efficient cellular uptake and transfection. This application is promising for treating genetic disorders and developing advanced therapeutic strategies.
Additionally, it is employed in diagnostic imaging as a contrast agent carrier. Its ability to attach imaging probes enhances the sensitivity and specificity of imaging techniques, such as MRI or fluorescence imaging, aiding in early disease detection and monitoring.
In materials science, it is used to modify surfaces or create nanocomposites, improving properties like adhesion, stability, or conductivity. Its versatility and tunable structure make it a valuable tool in nanotechnology and advanced material design.
format_list_bulleted Product Specification
Test Parameter | Specification |
---|---|
Appearance | liquid |
Concentration | 20% |
Infrared Spectrum | Conforms to Structure |
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PAMAM dendrimer, ethylenediamine core, generation 4.0 solution
PAMAM dendrimer, ethylenediamine core, generation 4.0 solution, is widely used in drug delivery systems due to its ability to encapsulate and transport therapeutic agents. Its highly branched structure allows for efficient loading of drugs, while its surface functional groups can be tailored for targeted delivery to specific cells or tissues. This makes it particularly useful in cancer therapy, where precise delivery of chemotherapeutic agents is critical to minimize side effects.
In gene therapy, it serves as a non-viral vector for delivering nucleic acids, such as DNA or RNA, into cells. Its positive surface charge facilitates binding with negatively charged genetic material, enabling efficient cellular uptake and transfection. This application is promising for treating genetic disorders and developing advanced therapeutic strategies.
Additionally, it is employed in diagnostic imaging as a contrast agent carrier. Its ability to attach imaging probes enhances the sensitivity and specificity of imaging techniques, such as MRI or fluorescence imaging, aiding in early disease detection and monitoring.
In materials science, it is used to modify surfaces or create nanocomposites, improving properties like adhesion, stability, or conductivity. Its versatility and tunable structure make it a valuable tool in nanotechnology and advanced material design.
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