5-MAPB hydrochloride is primarily used in research settings to study its effects on serotonin, dopamine, and norepinephrine systems due to its entactogenic and stimulant properties. It is often explored for its potential to induce feelings of empathy, emotional openness, and euphoria, making it a subject of interest in neuropharmacology and behavioral studies. Researchers investigate its interactions with neurotransmitter transporters and receptors to better understand its mechanisms and potential therapeutic applications. Additionally, it is sometimes used in the study of substance abuse and addiction, providing insights into the effects of psychoactive substances on the brain. Its use is strictly limited to controlled scientific environments to ensure safety and compliance with regulatory standards.