IU1-47 is primarily utilized in biochemical research as a selective inhibitor of the deubiquitinating enzyme USP14. This compound is instrumental in studying the ubiquitin-proteasome system, which plays a critical role in protein degradation and cellular regulation. By inhibiting USP14, IU1-47 helps researchers understand the enzyme's function in protein turnover, cellular stress responses, and its potential implications in diseases such as cancer and neurodegenerative disorders. Its application extends to exploring therapeutic targets, as modulating USP14 activity could offer new avenues for treating conditions associated with protein misfolding or impaired degradation pathways.