USP7/USP47 inhibitors are primarily used in cancer research and therapy. They target and inhibit the deubiquitinating enzymes USP7 and USP47, which play a role in regulating protein stability and function. By inhibiting these enzymes, the inhibitors can disrupt pathways that promote tumor growth and survival, particularly in cancers where these enzymes are overactive. This makes them valuable tools in studying cancer biology and developing targeted treatments. Additionally, they are explored for their potential in neurodegenerative diseases, as USP7/USP47 are involved in protein aggregation processes linked to conditions like Alzheimer's and Parkinson's. Their application extends to drug discovery, where they are used to identify novel therapeutic targets and validate their role in disease mechanisms.