Used in research as a deuterated analog of aloe-emodin, it serves as an internal standard in analytical methods like mass spectrometry and HPLC for accurate quantification of aloe-emodin in biological samples. Its application aids in studying pharmacokinetics, metabolism, and bioavailability of aloe-emodin in various studies. Additionally, it is valuable in exploring the biological activities and potential therapeutic effects of aloe-emodin derivatives.