(Bromodifluoromethyl)triphenylphosphonium Bromide

≥95%

Reagent Code: #154925
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CAS Number 58201-66-4

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scatter_plot Molecular Information
Weight 472.1 g/mol
Formula C₁₉H₁₅Br₂F₂P
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MDL Number MFCD00191843
inventory_2 Storage & Handling
Storage 2-8°C, light-proof, inert gas

description Product Description

Used as a reagent in organic synthesis for the introduction of the bromodifluoromethyl group (–CF2Br) into organic molecules. This transformation is valuable in the preparation of fluorinated compounds that serve as intermediates in pharmaceuticals, agrochemicals, and materials science. The phosphonium salt facilitates the formation of difluorocarbene or related species under basic conditions, enabling efficient C–H difluoromethylation or cyclopropanation reactions. Its utility in generating fluorinated building blocks makes it particularly important in medicinal chemistry for modulating the metabolic stability, lipophilicity, and bioavailability of drug candidates.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿17,000.00

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