SPDP-PEG4-COOH
95%
Reagent
Code: #106427
CAS Number
581065-97-6
blur_circular Chemical Specifications
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Molecular Information
Weight
462.58 g/mol
Formula
C₁₉H₃₀N₂O₇S₂
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Storage & Handling
Storage
2-8°C, dry, sealed
description Product Description
SPDP-PEG4-COOH is widely used in bioconjugation and protein modification due to its ability to link molecules through amine and thiol groups. The SPDP moiety allows for selective crosslinking with thiol-containing molecules, while the PEG4 spacer enhances solubility and reduces steric hindrance, making it ideal for creating stable and functional conjugates. This compound is particularly useful in antibody-drug conjugates (ADCs), where it facilitates the attachment of cytotoxic drugs to antibodies, improving targeted drug delivery. Additionally, it is employed in the development of peptide and protein-based therapeutics, enabling precise modifications to enhance stability, bioavailability, or targeting capabilities. Its application extends to diagnostic tools, where it aids in labeling biomolecules for imaging or detection purposes.
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SPDP-PEG4-COOH
SPDP-PEG4-COOH is widely used in bioconjugation and protein modification due to its ability to link molecules through amine and thiol groups. The SPDP moiety allows for selective crosslinking with thiol-containing molecules, while the PEG4 spacer enhances solubility and reduces steric hindrance, making it ideal for creating stable and functional conjugates. This compound is particularly useful in antibody-drug conjugates (ADCs), where it facilitates the attachment of cytotoxic drugs to antibodies, improving targeted drug delivery. Additionally, it is employed in the development of peptide and protein-based therapeutics, enabling precise modifications to enhance stability, bioavailability, or targeting capabilities. Its application extends to diagnostic tools, where it aids in labeling biomolecules for imaging or detection purposes.
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